ブランド: Tasigna
製造元: Novartis
病衣: Blood Cancer Called Philadelphia Chromosome Positive Chronic Myeloid Leukemia
ブランド: Tasigna
製造元: Novartis
病衣: Blood Cancer Called Philadelphia Chromosome Positive Chronic Myeloid Leukemia
Nilotinib is a cancer medicine that interferes with the growth and spread of cancer cells in the body.
Nilotinib is used to treat a type of blood cancer called Philadelphia chromosome positive chronic myeloid leukemia (CML) in adults and children who are at least 1 year old.
Nilotinib is usually given after other medications have been tried without success.
Nilotinib may also be used for purposes not listed in this medication guide.
You should not use nilotinib if you have long QT syndrome, or low blood levels of potassium or magnesium.
Nilotinib can cause a serious heart problem, especially if you use certain other medicines at the same time. Tell your doctor about all your other medicines. Your heart function may need to be checked before and during treatment with nilotinib.
Call your doctor right away or get emergency medical help if you have fast or pounding heartbeats and sudden dizziness (like you might pass out).
Avoid eating anything for at least 2 hours before and 1 hour after you take nilotinib.
You should not use nilotinib if you are allergic to it, or if you have:
Tell your doctor if you have ever had:
heart disease, heartbeat problems, or long QT syndrome (in you or a family member);
a stroke;
You may need to have a negative pregnancy test before starting this treatment.
Do not use nilotinib if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using nilotinib and for at least 14 days after your last dose.
Do not breast-feed while you are taking nilotinib and for at least 14 days after your last dose.
Nilotinib is usually taken every 12 hours. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Take nilotinib on an empty stomach, at least 1 hour before or 2 hours after a meal. Do not take with food. Food can increase your blood levels of nilotinib and may increase harmful side effects.
Take this medicine with a full glass of water. Swallow the capsule whole.
If you cannot swallow a capsule whole, open it and sprinkle the medicine into a teaspoon of applesauce. Swallow the mixture right away without chewing. Do not save it for later use.
Avoid eating anything for at least 2 hours before and 1 hour after you take nilotinib.
Nilotinib is to be taken long-term. You should not stop using nilotinib unless your doctor tells you to.
Nilotinib can lower your blood cell counts. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results.
Nilotinib can cause a serious heart problem. Your heart function may be checked with an electrocardiograph or ECG (sometimes called an EKG) before and during your treatment with nilotinib.
Store at room temperature away from moisture and heat.
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
Overdose symptoms may include drowsiness and vomiting.
Grapefruit may interact with nilotinib and lead to unwanted side effects. Avoid the use of grapefruit products.
Avoid taking a stomach acid reducer (such as Pepcid, Tagamet, or Zantac) within 10 hours before or 2 hours after you take nilotinib.
Avoid taking an antacid that contains aluminum, magnesium, or simethicone (such as Di-Gel, Gaviscon, Maalox, Milk of Magnesia, Mylanta, or Rolaids) within 2 hours before or 2 hours after you take nilotinib.
Nilotinib can pass into body fluids (urine, feces, vomit). Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Contact your doctor right away or get emergency medical help if you have symptoms of a serious heart problem: fast or pounding heartbeats and sudden dizziness (like you might pass out).
Call your doctor at once if you have:
Nilotinib can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using nilotinib.
Common side effects may include:
人々は、体の内部時計を調節するために、メラトニンを使います。予定が毎日の仕事を変える人々で睡眠覚醒循環を調節するために、それが時差ぼけのために使われます。それが、盲人が1昼夜サイクルを確立するのを援助するために使われます。メラトニンが、寝入る(不眠症)ことができないことのためにも、使われます; 遅延性睡眠段階症候群(DSPS); 急速眼球運動睡眠行動障害(RBD); 注意力欠陥-活動亢進障害(ADHD)を伴う不眠症; 特定の高血圧薬物による不眠症は、ベータ受容体遮断薬を呼びました; そして、自閉症、脳性麻痺と知的な障害を含む発達上の障害の子供たちの睡眠問題。ベンゾジアゼピン薬の用法をやめた後に、そして、禁煙する副作用を減らすために、それが睡眠援助としても使われます。一部の人々は、アルツハイマー病または記憶喪失(痴呆)のためにメラトニンを使います。障害、慢性閉塞性肺疾患(COPD)と呼ばれている肺疾患、ベータ受容体遮断薬薬に起因する不眠症、子宮内膜症のために、一部の人々はメラトニンを使います。そして、耳、落ち込みまたは季節性感情障害(SAD)、軽い精神的欠陥、アルコールを含まない肝疾患、慢性疲労症候群(CFS)、線維筋痛、絶え間ない足症候群を取り囲みます。そして、炎症性病気がサルコイドーシス、精神分裂症、片頭痛と他頭痛、年齢に関連する視力損失、良性前立腺過形成(BPH)、過敏性大腸症候群(IBS)、骨損失(骨粗鬆症)、遅行性顔面麻痺(TD)と呼ばれている運動障害と呼ばれています。酸性の逆流病、ヘリコバクターピロリ(H. pylori)、運動パフォーマンス、不妊性、癲癇、手術後の回復、麻酔に起因する動揺、ストレス、不随意運動障害(遅行性顔面麻痺)、定めることから体を起こす(姿勢の心搏急速症候群)ことに、貴社が移る心拍数の変化、精神錯乱、排尿をコントロールすることができないこと、あごの痛み、炎症性腸疾患(潰瘍性大腸炎)のための更年期(メタボリックシンドローム)のために、老化のために、そして、産児制限のために、一部の人々は、メラトニンを使います。 ... 詳細
3mg