Tecfidera is a prescription medicine used to treat relapsing forms of multiple sclerosis in adults (including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease).
Tecfidera is available as hard gelatin delayed-release capsules in two strengths containing either 120 mg or 240 mg of dimethyl fumarate.
It is not known if Tecfidera is safe and effective in children under 18 years of age.
Before taking and while you take Tecfidera, tell your doctor if you have or have had a low white blood cell counts or an infection.
Tecfidera may cause a serious viral infection of the brain that can lead to disability or death. Call your doctor right away if you have any change in your mental state, decreased vision, weakness on one side of your body, or problems with speech or walking. These symptoms may start gradually and get worse quickly.
You should not use Tecfidera if you have had a severe allergic reaction to dimethyl fumarate or diroximel fumarate (Vumerity).
To make sure Tecfidera is safe for you, tell your doctor if you have ever had:
• an active infection; or
• low white blood cell (WBC) counts.
Tell your doctor if you are pregnant or breastfeeding.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of dimethyl fumarate on the baby.
Tecfidera is not approved for use by anyone younger than 18 years old.
Take Tecfidera exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using Tecfidera.
You may take Tecfidera with or without food. Taking the medicine with food may help prevent flushing (sudden warmth, redness, or tingly feeling).
Swallow the capsule whole and do not crush, chew, break, or open it.
While using this medicine, you will need frequent blood tests.
Store this medicine in the original container at room temperature, away from moisture, heat, and light.
Get emergency medical help if you have signs of an allergic reaction to Tecfidera: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Dimethyl fumarate may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly.
Also call your doctor at once if you have:
• symptoms of herpes virus - flu-like symptoms, cold sores around your mouth, tingly or painful blistering rash, burning pain in your thigh or lower back;
• low white blood cell counts - fever, mouth sores, skin sores, sore throat, cough, trouble breathing; or
• liver problems - loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Common Tecfidera side effects include:
• stomach pain, indigestion, nausea, vomiting, diarrhea;
• redness, rash, itching; or
• flushing (sudden warmth, redness, or tingly feeling).
Other drugs may interact with dimethyl fumarate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
人々は、体の内部時計を調節するために、メラトニンを使います。予定が毎日の仕事を変える人々で睡眠覚醒循環を調節するために、それが時差ぼけのために使われます。それが、盲人が1昼夜サイクルを確立するのを援助するために使われます。メラトニンが、寝入る(不眠症)ことができないことのためにも、使われます; 遅延性睡眠段階症候群(DSPS); 急速眼球運動睡眠行動障害(RBD); 注意力欠陥-活動亢進障害(ADHD)を伴う不眠症; 特定の高血圧薬物による不眠症は、ベータ受容体遮断薬を呼びました; そして、自閉症、脳性麻痺と知的な障害を含む発達上の障害の子供たちの睡眠問題。ベンゾジアゼピン薬の用法をやめた後に、そして、禁煙する副作用を減らすために、それが睡眠援助としても使われます。一部の人々は、アルツハイマー病または記憶喪失(痴呆)のためにメラトニンを使います。障害、慢性閉塞性肺疾患(COPD)と呼ばれている肺疾患、ベータ受容体遮断薬薬に起因する不眠症、子宮内膜症のために、一部の人々はメラトニンを使います。そして、耳、落ち込みまたは季節性感情障害(SAD)、軽い精神的欠陥、アルコールを含まない肝疾患、慢性疲労症候群(CFS)、線維筋痛、絶え間ない足症候群を取り囲みます。そして、炎症性病気がサルコイドーシス、精神分裂症、片頭痛と他頭痛、年齢に関連する視力損失、良性前立腺過形成(BPH)、過敏性大腸症候群(IBS)、骨損失(骨粗鬆症)、遅行性顔面麻痺(TD)と呼ばれている運動障害と呼ばれています。酸性の逆流病、ヘリコバクターピロリ(H. pylori)、運動パフォーマンス、不妊性、癲癇、手術後の回復、麻酔に起因する動揺、ストレス、不随意運動障害(遅行性顔面麻痺)、定めることから体を起こす(姿勢の心搏急速症候群)ことに、貴社が移る心拍数の変化、精神錯乱、排尿をコントロールすることができないこと、あごの痛み、炎症性腸疾患(潰瘍性大腸炎)のための更年期(メタボリックシンドローム)のために、老化のために、そして、産児制限のために、一部の人々は、メラトニンを使います。 ... 詳細
3mg